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Quantitative MRI Application being developed to help prevent vision loss in NF1 patients

17 July 2019

Quantitative MRI Application being developed to help prevent vision loss in NF1 patients

The following has been taken from Health Data Management's website

"A Children’s National researcher, Marius George Linguraru, has been awarded a Congressionally Directed Medical Research Program grant through the Department of Defense. This grant enables Linguraru to develop a quantitative MRI application that can inform treatment decisions by accurately identifying which children with neurofibromatosis type 1 (NF1) and optic pathway glioma (OPG) are at risk of losing their vision

This project will provide doctors with certainty when identifying which children with NF1-OPG will lose vision—and when the vision loss will occur—through computational modeling validated in clinics worldwide. Using Linguraru's technology, diagnosis can occur before visual acuity starts to decline, providing an opportunity for early intervention in children at risk for vision loss.

Early diagnosis and treatment can help to avoid lifelong visual impairment for patients who need intervention while preventing unnecessary MRIs and aggressive chemotherapy in pediatric patients who are not at risk of vision loss."

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